Candida
species, the most dominant of which are Candida
Albicans, are a normal oral commensally that is present
among 30% - 60% of healthy individuals. Colonization of
oral surfaces can serve as a reservoir for yeasts`
multiplication and disseminated infections. However, the
presence of yeasts in the oral cavity does not
necessarily lead to oral yeast infection.
Oral
candidiasis develops under some predisposing conditions,
such as:
·
Systemic
diseases affecting host defenses.
·
Drug
therapies that affect the host’s defenses and cause
changes in the oral cavity.
·
Antibiotic
therapies that disrupt the normal inner balance of
organisms in the intestines by the elimination of the
beneficial gastrointestinal bacterial flora that
normally help to prevent Candida
multiplication.
·
Physiologic
conditions such as aging, pregnancy, infancy, dietary
factors, iron deficiencies, diseases like diabetes,
hypothyroidism , hypoadrenalism
etc.
·
Oral
exposure to yeast infection contributors, such as
medications, vitamin or mineral deficiencies, allergies
to foods or food additives, oral irritation
etc.
·
Psychological
factors such as stress, depression or
anxiety.
·
Local
factors, such as wearing dentures as dentures can
trigger oral Candida cultivation (old dentures with
porosity can result in poor mouth hygiene, promoting
yeast colonization).
Secondly,
since saliva hardly flows underneath dentures, its
mechanical washing effect is absent. Thus, the median
prevalence of yeast organisms was found to be 37% in the
saliva of subjects with natural teeth and 85% in denture
wearers with clinically normal palatal
mucosa.
Other
conditions that affect salivary flow, such as Sjogren’s
syndrome and some types of antidepressants, can
contribute to Candidiasis predisposition as
well.
The
most common symptoms of oral yeast infection
are:
·
White,
creamy or yellow spots with red background that appear
in the inner surface of the mouth. Aggressive scrubbing
will result in bleeding rather then their
elimination.
·
Extra
tissue that cannot be wiped off
(hyperplastic).
·
Redness
in the tongue with no bright spots, sometimes followed
by peeling patches on the surface of the
tongue.
·
Red
cracks at the corners if the mouth (angular
cheilitis).
Alongside
with its visible symptoms, oral candidiasis can be
accompanied by an unpleasant burning sensation in the
infected area.
Oral
thrush is extremely common in newborn babies. In
newborns, restlessness and anger during feedings, as
well as sudden refusal to take a pacifier, serve as the
first evidence for oral yeast infection, which demands
further tests.
Oral
yeast infection can be effectively treated with some
anti – fungal drugs, such as:
·
Nystatin
(brand names: mycostatin, mycolog and nilstat): An
antibiotic used for different subtypes of fungal
infections. It is non-toxic and doesn’t damage bacteria
or viruses. In the case of oral yeast infection, it can
be taken by mouth as a tablet or a liquid three to five
times a day. Oral yeast infection usually disappears
after 48 hours of using this medication. Note that this
drug requires multiple doses, which can lower the
patient compliance.
·
Ketoconazole
(brand names: mycelex, monistat and nizoral): an
antifungal that alters the fungus cell wall while
eliminating fungi organisms.
·
Triazole
antifungal agents, such as itraconazole and fluconazole.
Itraconazole may be taken orally or intravenously as
part of a continuous treatment (at least three months,
until a laboratory test results find no fungal
infections). Itraconazole’s main disadvantages are poor
absorption and various side effects, such as nausea,
vomiting, abdominal pain, fatigue etc. Fluconazole comes
as a tablet or a liquid and is to be taken orally once a
day for several weeks or longer.
·
Amphotericin
B (brand names: fungizone, adria and apothecon): polyene
antimycotic drug, a powerful antibiotic for treatment of
fungal infections. This drug is usually prescribed for
the treatment of severe candidiasis and given during
hospitalization. This drug exhibits toxicity and may
cause a variety of side effects.
In
addition to prescription medication and OTCs, there is a
rich selection of alternative remedies for oral yeast
infection, such as herbal and homeopathic remedies,
alongside complete all natural holistic
treatments.